Program
Thursday March 13 2008
8h30 - Registration
SESSION 1: Scientific Vision of Nutrigenomics: Actual State and Recent Advances
Chairmen: Pr Claudine Junien, Dr Sian Astley
9:00 - Food-genes interactions and long-term health: Challenges for science, industry & society
Dr Siân Astley, European Communications manager, Norwish Biosciences Institutes, Norwish, UK
9:30 - The future of food and the food of future: What Nutrigenomics brings?
How diet affect genes expression
How these changes influence protein expression and metabolism?
Genetics variation & individual physiological response to diet
How to determine the effective dose?
Pr Lydia Afman, Metabolism and Genomics Group, Wageningen University, The Netherlands
10:00 Nutri-epigenomics: Lifelong Impact of diet on epigenome remodelling and beyond
Pr Claudine Junien, INSERM U781 - Génétique et Epigénétique des Maladies Métaboliques, Neurosensorielles et du Développement, France
10h30 - Break and Poster Session
NutriGenomics & Chronic Diseases Prevention
11:00 - Nutrigenomics can deliver biomarkers for dietary intervention and individual disposition
Dr Martin Kussmann, Nestlé Research Center, Lausanne, Switzerland
11:30 - Overview on Nutrigenomics & chronic diseases prevention: Obesity & Diabetes: Potentials and challenges
Dr Amelia Marti, Department of Physiology and Nutrition, University of Navarra, Pamplona, Spain
12:00 - Genomics view of ageing and longevity: Two sides of the coin
Perspectives of Nutrigenomics in anti-aging strategies
Can nutrition slow down the overall skin aging process?
Do the personalisation of diet and cosmectics has to be updated through life-time?
Can Nutrigenomics contribute to define new cosmetic targets?
Dr Elena Baranova, President of the European Institute of Personalised Prevention, France
12h30 - Lunch and Poster Session
Chairmen: Dr Ramon Cacabelos, Lydia Afman, John Hesketh
14:00 - Antioxidant absorption and genes: Antioxidant intake related to genetic polymorphisms?
Can Nutrigenetic modulates antioxydant recommendations?
Dr Patrick Borel, UMR 476 INSERM/ 1260 INRA, Faculté de Médecine de Marseille, France
14:30 - Nutrigenomics and Selenium: Do genetic factors influence selenium metabolism and nutritional requirements?
What biomarkers are available to study selenium incorporation?
Is there individual variation regarding selenoproteins synthesis?
Pr John Hesketh, Institute for Cell and Molecular Biosciences, University of Newcastle upon Tyne, United Kingdom
15:00 - Pharmacogenomics, Nutrigenomics and therapeutic optimization : The case of Alzheimer's disease
Dr Ramon Cacabelos, BioEspes Biomedical Research center, Bergondo, Coruna, Spain
15:30 - Break & Poster Session
16:00 - Short oral communications
- PPARΑ is essentil for utilization of plant diets
K. Motojima et al., Department of Biochemistry, Meiji Pharmaceutical University, Tokyo, Japan - Association between ICAM-1 and VCAM-1 polymorphisms and serum levels of cell adhesion molecules: Modulation by the red wine consumption
O. Portolés et al., Department of Preventive Medicine. University of Valencia, Spain - Targeting heat shock protein and inflammatory profile through nutraceutical intervention: The role of IL-6 polymorphims
F. Marotta et al., Consultant in Gastroenterology, WHO center for Biotech & National Med, University of Milano, Italy - Human in Vivo Nutrigenomic effect of olive oil
V. Konstantinidou, Lipids and Cardiovascular Epidemiology Research Unit, IMIM Hospital del Mar, Barcelona, Spain - Serum 25 hydroxyvitamin D and IGE – A significant but non linear relationship
E. Hyppönen et al., MRC Centre for Epidemiology of Child Health, London, UK - Genes, nutrition and metabolic syndrome prevention.
I. Wybranska et al., Dept of Clinical Biochemistry, The Jagiellonian University Medical College, Krakow,Kopernika - Genetic variants in hepatic lipase, aPOb and I-FABP are associated with human plasma levels of Vitamin E and carotenoids
M. Moussa et al, INRA, Nutriments Lipidiques et Prévention des Maladies Métaboliques, Marseille, France - Metabolic alterations and response to weight-loss intervention vary with perilipin polymorphisms in obese children and adolescents
Sophie Deram et al., Laboratory of Human Nutrition and Metabolic Disease – LIM-25, FMUSP: University of São Paulo Medical School – Brazil - Effect of milk fermentation on global gene expression in human blood cells
M.F. Sagaya et al., Laboratory for Human Nutrition, Swiss Federal Institute of Technology Zurich (ETHZ), Switzerland - Personalized nutrition? Gene-diet interaction in intervention studies
R. valls et al., Unitat de recerca de lípids i arteriosclerosis, facultat de medicina i ciències de la salut. Hospital universitari sant joan, Spain
16:30 - Discussion & end of the day
19:00 - Pick up for Gala Dinner at Le Capitaine Fracasse
The Gala dinner will be held on the Seine, on board of the cruising restaurant boat "Le Capitaine Fracasse" More Information : www.lecapitainefracasse.com
Pick up at the entrance of 15 rue de l'école de médecine and return back at 23h at the same place
Friday March 14 2008
SESSION 2: Industrial vision of Nutrigenomics: Innovations, perspectives & limits
9:00 - New tools and technologies development in Nutrigenomics
Dr Ruan Elliott, Institute of Food Research, Norwich Research Park, United Kingdom
9:30 - Metabolomics impact on nutritional research: Innovations & Trends
Principles: What are the actual tools for metabolomics research?
Limits: How face the difficulty of data analysis and interpretation?
Applications: What are the perspectives for metabolomics in nutrition?
Future: Can metabolomics tests become “routine” tests?
Dr James Kinross, Imperial College of London, London, United Kingdom
10:00 - Nutrigenomics & Ethic-legal-social issues
How consumers select food? Sociological aspects of eating
Consumers’ information & acceptance of Nutrigenomics
Genetic profiling & personal DNA analysis: Privacy concerns
Pr Ulf Görman, Department for Ethics, Lund University, Sweden
10h30 - Break and Poster Session
11:00 - Short oral communications
Last advances and new developments in the field of Nutrigenomics:
Health ingredients, Functional foods and drinks
Innovative materials addressed to researchers and research laboratories
Selected communications:
- Metabolite Profiling and its Applications in Nutrition Product and Biomarker Development
S. Kass, Managing Director Metanomics Health, Berlin, Germany - Nutriproteomics Approach To Interpret The Biological Effect Of Soybean Isoflavone In Cell Fate Determination
K. Yoshida, Department of Life Sciences, Meiji University School of Agriculture, Kawasaki, Japan - The Cellular Basis for the Efficacy of Celadrin in the Treatment of Joint Pain and Discomfort
R. Hesslink, Sc.D., Director, Research & Development, Imagenetix, Inc., San Diego, USA - In silico prediction of the activator activity of naturally occurring and bioactive forms of phenolic compounds on the Farnesoid X Receptor
C. Blade & al., Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, Tarragona, Spain - Lactoferrin-Enriched Milk Protects Neonatal from a Lethal Challenge with Enterovirus Type 71
C-M Chen & al., Department of Life Sciences, National Chung Hsing University, Taichung, Taiwan
12:00 - Roundtable discussion in the presence of speakers & the scientific committee
Personalized nutrition: New wave for disease prevention and wellbeing: science or fiction?
Synergies and confrontations between the scientific & industrial visions of Nutrigenomics and the place of the consumer
12:40 Conclusion by Dr Marvin Edeas the chairman of the scientific committtee
12h45 - Poster session
- Antioxidant activity of Quercus suber leaf extracts
C. Santos et al, Disease and Stress Biology Laboratory, Oeiras, Portugal - Tri E tocotrienol supplementation reduced DNA damage and improved oxidative status in healthy older adults
W. Ngah et al., Department of Biochemistry, Medical Faculty, Universiti Kebangsaan, Malaysia - Anticancer effect of chlorella vulgaris hot water extract via apoptosis signaling pathway
Y. Yusof et al., Department of Biochemistry, Medical Faculty, Universiti Kebangsaan, Malaysia - Proanthocyanidins increase gene expression of UCP-1 in mitochondria of brown adipose tissues of obese rats
D. Pajuelo et al., Nutrigenomics Group. Department of Biochemistry and Biotechnology. Rovira i Virgili University. - Effect of gamma-tocotrienol and alfa-tocoferol on proteins of the apoptotic pathway in neurons
M. Mazlan et al., Department of Biochemistry, Medical Faculty, Universiti Kebangsaan, Malaysia - Depletion of intracellular zinc induces down-regulation of Uch-L1 and CREB in cultured hippocampal neurons
Y.G. Jiang, Institute of Hygiene & Environmental Medicine, Tianjin, P.R China - A Proprietary Mixture of Modified Cellulose May Reduce the Risk for Metabolic Syndrome by Altering Substrate Utilization in the Liver and Skeletal Muscle
Robert Hesslink, Sc.D., Director, Research and Development, Imagenetix, Inc., San Diego, CA, USA - Antioxydants in Nutrition and health
S.b. pajovic et al., Laboratory of Molecular Biology and Endocrinology, Vinča Institute of Nuclear Sciences,Belgrade, Serbia - Proanthocyanidins increase gene expression of UCP-1 in mitochondria of brown adipose tissues of obese rats
D. Pajuelo et al., Nutrigenomics Group. Department of Biochemistry and Biotechnology. Rovira i Virgili University. - Methylmetabolomic approach of genomic instability linked with dna hypomethylation biomarkers
I. Turcu et al., University of Bucharest, Faculty of Biology, Dept of Genetics –Microgen – Epigenetics laboratory, Romania - Adipose tissue lipin-1β expression is positively correlated with carnitine-palmitoyl transferase 1b expression in lean and obese subjects
T Lappalainenet al., Dept of Clinical Nutrition/Food and Health Research Centre, University of Kuopio, Finland - Proanthocyanidins improve the proatheraogenic profile of Huge Cells
S. Díazet al. Nutrigenomics Group. Department of Biochemistry and Biotechnology. Rovira i Virgili University, Spain - Innovativeness of the Polish Food Sector – Links between Industry and Science
I. Szczepaniak, M. Wigier, National Research Institute of Agricultural and Food Economics (IERiGŻ-PIB),Warsaw, Poland - Single nucleotide polymorphisms in MYO9B and Gluten Allergy Incidence in A Crohn’s Disease Population in New Zealand
P.A. Dryland et al., Discipline of Nutrition, Faculty of Medical & Health Sciences, The University of Auckland, Auckland, New Zealand - Micro-array ANALYSIS of gene expression in obesity: identification of potential targets for nutritional interventions
D. De Groote et al., PROBIOX SA, Campus Universitaire du Sart-Tilman, Liège Belgium - Effects of Functional Foods With Vegetal Bioactive Ingredients In The Metabolic Syndrome
S Dragan et al., University of Medicine and Pharmacy Timisoara, Romania - Genetic predisposition to metabolic desorders and young athletes’ nutrition
N.D Golberg et al., St-Petersburg Research Institute of Physical Culture, St. Petersburg, Russia - Action of royal jelly in the cell
P. Jamnik et al., University of Ljubljana, Biotechnical Faculty, Food Science and Technology Department, Chair of Biotechnology, Ljubljana, Slovenia - Grape-seed derived procyanidins normalize adiponectinemia on high-fat diet induced obesity
G. Montagut et al., Dept de Bioquímica i Biotecnologia. Universitat Rovira i Virgili, Tarragona, Spain - Foods Rich in Polyphenols and N-3 fatty acids decrease cutaneaous melanoma risk
C. Fortes, Clinical Epidemiology Unit, IDI, Roma, Italia - Use of a bioreactor to effect the controlled fermentation of goat’s milk via Bifidobacterium animalis and Lactobacillus acidophilus
M. Kongo, Departamento de Biologia, Unversidad dos Açores, Portugal - Proanthocyanidins improve triglyceride metabolism in obese rats
H. Quesada et al., Nutrigenomics Group. Department of Biochemistry and Biotechnology. Rovira i Virgili University
